BDBM50439517 CHEMBL2418349
SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOC[C@@H]2CC)c2n(C)ncc2n1
InChI Key InChIKey=DFFHBQFOKXDZFK-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50439517
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant mTOR (1360-2549) expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 after 30 mins by L...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR in PTEN deficient human PC3 cells assessed as inhibition of Akt phosphorylation at Ser473More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mTOR in PTEN deficient human PC3 cells assessed as inhibition of p70S6K phosphorylationMore data for this Ligand-Target Pair